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MTOR — NPY6R
Text-mined interactions from Literome
Krauss et al., Cancer Res 2008
(Neoplasms) :
Here, we show that protein
phosphatase 2A (PP2A) , its regulatory subunit, alpha4, and rapamycin, an
inhibitor of the
mammalian target of rapamycin kinase complex 1 ( mTORC1 ), regulate the nuclear localization and transcriptional activity of GLI3
Lee et al., Cell Mol Life Sci 2009
:
Galectin-1 induced phospho-Akt and
-mTOR was
inhibited by
PP2 , ERas siRNA, caveolin-1 siRNA and Mbeta-CD
Magnaudeix et al., Neurobiol Aging 2013
:
In addition,
PP2A blockade
resulted in the activation of the negative regulator of autophagy
mammalian target of rapamycin complex 1 and 5 ' adenosine monophosphate ( AMP ) -activated protein kinase ( AMPK ) and led to intraneuronal accumulation of p62- and ubiquitin positive protein inclusions, likely due to autophagy downregulation