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ACAN — FGF1

Text-mined interactions from Literome

Sandell et al., Osteoarthritis Cartilage 2008 (Arthritis) : In the presence of IL-1beta, FGF-18 increased expression of ADAMTS-4, aggrecan , BMP-2, COL2A1, CCL3, CCL4, CCL20, CXCL1, CXCL3, CXCL6, IL-1beta, IL-6, and IL-8 and decreased ADAMTS-5, MMP-13, CCL2, and CCL8
Chandrasekhar et al., Agents Actions Suppl 1993 : Finally, with respect to proteoglycan synthesis, TGF-beta, PDGF and IGF-1 reversed IL-1 induced PG suppression to different extents, while FGF slightly potentiated IL-1 induced suppression of aggrecan synthesis