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ATF1 — MAPK13
Text-mined interactions from Literome
Yosimichi et al., Eur J Biochem 2001
:
These inhibitors of MAPKK and
MAPK suppressed phosphorylation of ets-like gene-1 (Elk-1) and nuclear
activating transcription factor-2 ( Atf-2 ) induced by CTGF/Hcs24 in a dose dependent manner, respectively
Ghosh et al., J Biol Chem 2002
:
Regardless of this, inhibition of p38
MAPK reduced only thrombin- but not PDGF-BB induced
ATF-1 phosphorylation ... 1 ) Both RTK and GPCR agonists activate p38
MAPK and induce CRE promoter dependent transcription ; 2 ) both RTK and GPCR agonists
induce ATF-1 phosphorylation, and ATF-1 is a predominant member in the CRE-DNA complexes formed in response to these agents ; and 3 ) p38 MAPK dependent ATF-1 phosphorylation and CRE promoter mediated transcription are associated with GPCR agonist induced VSMC growth
Faour et al., J Biol Chem 2005
(Arthritis, Rheumatoid) :
Initial studies confirmed that PGE2 induces egr-1 mRNA expression and protein synthesis by restricted SAPK2/p38
MAPK dependent
activating transcription factor-2 ( ATF-2) dimer transactivation of the egr-1 promoter as judged by studies using wild-type ( WT ) and deletion mutant egr-1 promoter constructs, Northern and Western blotting, and standard and supershift electrophoretic mobility shift analyses
Cui et al., FASEB J 2006
:
Phosphorylation of
ATF-1 is
blocked by the p38
MAPK inhibitor SB 203580
Hisatsune et al., J Immunol 2008
:
Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent
role for
p38MAPK in
activating transcription factor-2 , cAMP response element binding protein, and NF-kappaB activation
Cho et al., Mol Endocrinol 2009
:
The inhibition of
MAPK dependent
activating transcription factor 2/c-Jun phosphorylation by GR in COX-2 repression was a result of MAPK phosphatase-1 (MKP-1) induction