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PTGS2 — RENBP

Text-mined interactions from Literome

Lin et al., Eur J Pharmacol 2002 : Taken together, our results suggest that activation of protein tyrosine kinase and p38 MAPK is involved in AGE induced cyclooxygenase-2 expression in RAW 264.7 macrophages
Locatelli et al., Nephrol Dial Transplant 2003 (Diabetes Complications...) : New treatment strategies are under investigation, including inhibitors of AGE formation, protein kinase C inhibitors, antioxidants, glycosaminoglycans, PPAR-gamma agonists and COX-2 inhibitors
Nah et al., Rheumatology (Oxford) 2008 (MAP Kinase Signaling System...) : Pre-treatment with soluble receptor for AGE ( sRAGE ) also reduced AGE stimulated COX-2 , iNOS and PGE ( 2 ), implicating the involvement of RAGE
Huang et al., Eur J Clin Invest 2009 (Osteoarthritis) : AGE potently induced COX-2-PGE ( 2 ) and iNOS-NO activation in porcine and human chondrocytes
Wu et al., Pharmacology 2013 : Results : Cariporide significantly suppressed AGE induced neointimal hyperplasia, vascular smooth muscle cell ( VSMC ) proliferation, COX-2 , MMP-2 and MMP-9 expression