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BMP2 — GPC1
Text-mined interactions from Literome
Kayed et al., Int J Oncol 2006
(Carcinoma, Pancreatic Ductal...) :
In view of the importance of members of the TGF-beta family in pancreatic cancer, in the present study, the
role of
GPC1 in TGF-beta,
BMP and activin signaling was analyzed
Dwivedi et al., Bone 2013
:
In contrast, increased levels of
GPC1 and GPC3 as a result of overexpression or the addition of recombinant protein,
inhibit BMP2 signalling and BMP2 mediated osteogenesis ... We demonstrate that
BMP signalling in suture mesenchymal cells is mediated by both SMAD dependent and SMAD independent pathways and that
GPC1 and GPC3
inhibit both pathways