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BMP2 — IL1A
Text-mined interactions from Literome
Fukui et al., J Bone Joint Surg Am 2003
(Osteoarthritis) :
In cartilage explant cultures,
IL-1beta and TNF-alpha
increased BMP-2 levels both intracellularly and extracellularly
Shi et al., Inflamm Res 2004
(Chondrosarcoma...) :
IL-1 , but not TNF-alpha, can
induce IL-6,
bone morphogenic protein 2 (BMP-2) , and cyclooxygenase ( COX-2 ) expression in SW1353 cells
Aida et al., Life Sci 2004
:
The expression of
BMP-2 was
increased at days 3, 7, and 14 of culture with
IL-1alpha , while the expression of type II receptor for BMP-2 was significantly decreased in the samples
Mumme et al., European cells & materials 2012
:
In osteogenically cultured BM-MSC,
IL-1ß enhanced calcium deposition ( 62.2-fold ) and
BMP-2 mRNA expression by differential activation of NF-?B and ERK signalling
Nakase et al., Bone 1997
:
The modulatory
effects of
interleukin (IL)-1 beta and tumor necrosis factor (TNF)-alpha on bone morphogenetic protein
(BMP)-2- and -4-induced alkaline phosphatase (ALP) activity were examined in cultures of mouse MC3T3-E1 osteoblastic cells