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BMP2 — JUNB
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
JUNB
→
BMP2
(increases, BMP2 Activity)
Evidence: he DNA binding activities of c-Fos, FosB/Delta FosB, Fra-1, Fra-2, and JunB were up-regulated whereas JunD activity was decreased.
Text-mined interactions from Literome
Hollnagel et al., J Biol Chem 1999
:
BMP2/4 rapidly
induced transcript levels of the homeobox genes Msx-1 and Msx-2 and the proto-oncogene
JunB , whereas c-jun transcripts displayed delayed albeit prolonged increase
Chalaux et al., J Biol Chem 1998
:
BMP-2 induces transcriptional activation of
JunB expression as early as 30 min after ligand addition, reaching maximal levels after 90 min. Increase of JunB mRNA correlates with a higher AP-1 binding activity