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BMP2 — MAPK1

Text-mined interactions from Literome

Viñals et al., FEBS Lett 2002 : In contrast, BMP-2 had no effect on p42/p44 MAPK ( Erks ) stimulation ... In contrast, BMP-2 had no effect on p42/p44 MAPK ( Erks ) stimulation
Guicheux et al., J Bone Miner Res 2003 (MAP Kinase Signaling System) : Activation of mitogen activated protein ( MAP ) kinases by BMP-2 and the role of these signaling pathways for cell differentiation induced by BMP-2 was investigated in mouse MC3T3-E1 and primary cultured calvaria derived osteoblastic cells using immunoprecipitation, in vitro kinase assay and Western blot analysis, as well as specific MAP kinase inhibitors
Scherberich et al., Oncogene 2005 (Breast Neoplasms...) : Tenascin-W is found in malignant mammary tumors, promotes alpha8 integrin dependent motility and requires p38MAPK activity for BMP-2 and TNF-alpha induced expression in vitro
Rifas et al., J Cell Biochem 2006 (Arthritis...) : Inhibition of p38 MAPK completely inhibited TTII induced BMP-2 production and matrix mineralization
Ghosh-Choudhury et al., J Biol Chem 2007 (MAP Kinase Signaling System) : Lovastatin induced Erk1/2 activity contributed to BMP-2 transcription
Zanotti et al., J Cell Biochem 2008 : Neither gremlin nor BMP-2 induced ERK 1/2 activation in ST-2 cells or calvarial osteoblasts
Maeda et al., J Biochem 2009 : Interestingly, CCN2-BMP-2 did not affect the BMP-2/CCN2 induced phosphorylation of p38 MAPK but caused less phosphorylation of ERK1/2 in cultured chondrocytes
Leong et al., PloS one 2009 (Osteoporosis) : These results indicate that protein palmitoylation plays an important role in BMP induced MAPK activation, osterix expression, and osteoblast differentiation
Yamanaka et al., Hypertens Res 2010 (Hypertension, Pulmonary) : Notably, ET1- and aldosterone induced mitosis and mitogen activated protein kinase phosphorylation were significantly increased in the presence of BMP-2 and BMP-7 in PASMCs isolated from idiopathic PAH, although additive effects were not observed in PASMCs isolated from secondary PAH
Ge et al., J Bone Miner Res 2012 (MAP Kinase Signaling System) : Significantly, in the presence of AA, BMP2/7 synergistically stimulated RUNX2 S319 phosphorylation and transcriptional activity without affecting total RUNX2 and this response was totally dependent on ERK/MAPK activity ... Significantly, in the presence of AA, BMP2/7 synergistically stimulated RUNX2 S319 phosphorylation and transcriptional activity without affecting total RUNX2 and this response was totally dependent on ERK/MAPK activity
Ebeling et al., Reprod Fertil Dev 2011 : Furthermore, BMP-6 did not affect the activity of the mitogen activated protein kinase
Moriyama et al., BMC cell biology 2012 : Inhibition of p38 MAPK was sufficient to suppress BMP2 and FGF2 expression, while this expression was significantly upregulated by overexpression of a constitutively active form of MKK6, which is an upstream molecule from p38 MAPK
Yumoto et al., J Biol Chem 2013 (Cleft Palate) : Our studies show that in neural crest derived craniofacial ecto-mesenchymal cells, Tak1 is not only required for TGF-ß- and bone morphogenetic protein induced p38 Mapk activation but also plays a role in agonist induced C-terminal and linker region phosphorylation of the receptor mediated R-Smads
Sabbieti et al., Endocrinology 2013 : BMP-2 caused a sustained increase in phospho-p38 MAPK in Tg ( Vector ) but only a transient increase in Tg ( LMW ) and Tg ( HMW ) COBs ... BMP-2 caused a transient increase in phospho-p44/42 MAPK in Tg ( Vector ) COBs and no increase in Tg ( LMW ) COBs, but a sustained increase was found in Tg ( HMW ) COBs
Guang et al., Int J Biochem Cell Biol 2013 : Mechanistically, impaired BMP2- or Dex-osteoinduction in BMSCs of elderly mice was mediated by inhibited phosphorylation of intracellular R-Smads and Erk1/2 or Erk1/2 and p38 proteins, and decreased Runx2 and Osx expression ( osteogenesis `` master '' regulators ) were also detected