Nakashima et al., Frontiers in bioscience : a journal and virtual library 2006
:
In these cultures, MMP-13 mRNA expression was induced by BMP-2 in Wnt3a over expressing C2C12 ( Wnt3a-C2C12 ) cells but not in either Wnt5a over expressing C2C12 ( Wnt5a-C2C12 ) cells or vehicle transfected C2C12 cells
Kumagai et al., Anticancer Res 2006
(Carcinoma...) :
Gel zymography for matrix metalloproteinases ( MMPs ) and urokinase-type plasminogen activator ( uPA ) detection revealed that BMP-2 down-regulated the activity of MMP-9 , but not of MMP-2 or uPA ... BMP-2 also reduced the secretion of MMP-9 into the culture media, but did not affect the secretion of MMP-2, Timp-1, Timp-2 or Timp-3
Fukui et al., Anat Rec (Hoboken) 2010
:
The aim of this study is to investigate whether BMP-2 regulates the oral sulcus formation of mouse embryonic tongue by modifying the expression of TIMP and MMP