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BMP2 — TCF3
Text-mined interactions from Literome
Dai et al., Dev Biol 2000
:
This is the first evidence that
Dpp/BMP signaling in flies
requires the direct interaction of Mad with a partner
transcription factor
Palcy et al., J Bone Miner Res 2000
:
Our data emphasize the
role of the AP-1
transcription factor in TGF-beta1 and
BMP-2 signaling and highlight the importance of this transcription factor family in the expression of OB genes
Feng et al., J Biol Chem 2003
:
Here we have used both in vitro and in vivo approaches to demonstrate that
transcription factor , NF-kappaB,
regulates BMP-2 gene expression in chondrocytes
Diefenderfer et al., J Bone Joint Surg Am 2003
:
We hypothesize that the mechanism by which BMPs modulate alkaline phosphatase expression is indirect, involving a
BMP regulated
transcription factor for alkaline phosphatase expression that is controlled differently in humans and rodents
Phimphilai et al., J Bone Miner Res 2006
:
This study shows that autocrine
BMP production is
necessary for the RUNX2
transcription factor to be active and that BMPs and RUNX2 cooperatively interact to stimulate osteoblast gene expression
Zhao et al., Mol Cell Biol 2006
:
The zinc finger
transcription factor Gli2
mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling
Ikeda et al., J Cell Biochem 2007
:
Identification of FAZF as a novel
BMP2 induced
transcription factor during osteoblastic differentiation
Goldring et al., Ann Rheum Dis 2008
(Osteoarthritis) :
These new genes include growth arrest and DNA damage ( GADD ) 45beta and the epithelial-specific ETS (ESE)-1
transcription factor ,
induced by
bone morphogenetic protein (BMP)-2 and inflammatory cytokines, respectively
Fan et al., J Cell Physiol 2009
:
Moreover,
BMP4 also
stimulated expression of
transcription factor -- C/EBP-alpha, which involved in differentiation of WB-F344 cells toward hepatocytes
Chae et al., BMB Rep 2009
:
Thus, the smpd3 promoter is activated by
BMP2 and is directly
regulated by the Runx2
transcription factor
Katoh et al., Int J Oncol 2009
:
Notch, BMP and Hedgehog signals inhibit WNT2B expression via HES/HEY binding to N-box, whereas
BMP and WNT signals
inhibit bHLH
transcription factor induced WNT2B expression via ID1, ID2, ID3, MSX1 or MSX2
Rajagopal et al., Dev Biol 2009
:
Lens formation, placode cell proliferation, the expression of FoxE3, a lens-specific
transcription factor , and the lens protein, alphaA-crystallin were
regulated by
BMP receptors in a Smad independent manner
Mandal et al., Calcif Tissue Int 2010
:
Osterix ( Osx ), a
BMP-2 regulated
transcription factor , controls expression of genes essential for osteoblast differentiation
Dummula et al., J Neurosci 2011
(Cerebral Hemorrhage...) :
Importantly,
BMP inhibition by recombinant human noggin
restored the levels of phospho-Smad1/5/8, Olig2
transcription factor , oligodendrocyte maturation, myelination, astrocyte morphology, and motor function in premature pups with IVH
Viale-Bouroncle et al., Stem Cells Dev 2012
:
This
transcription factor stimulates the osteogenic differentiation of DFCs and
regulates the
BMP/SMAD1-pathway
Chen et al., Biochem Biophys Res Commun 2012
:
Osterix ( Osx ) is a
bone morphogenetic protein 2 (BMP-2) inducible osteoblast-specific
transcription factor required for osteoblast differentiation and bone formation