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Sánchez-Alcázar et al., Lung Cancer 2003
(Carcinoma, Non-Small-Cell Lung...) :
These observations suggest that COX inhibitors induce apoptosis in non-small lung cancer cells through cytochrome c and AIF release, and subsequent caspase activation, independently of COX-2 expression and prostaglandin production
Laschke et al., Fertil Steril 2007
:
Moreover, COX-2 inhibition suppressed cell proliferation and induced apoptosis associated caspase-3 expression