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CASP3 — IGF1R

Text-mined interactions from Literome

Schlueter et al., Cell Death Differ 2007 : At the cellular level, IGF1R inhibition increased caspase 3 activity and induced neuronal apoptosis
Yang et al., BMC cancer 2009 (Colorectal Neoplasms) : Using three colorectal cancer cell lines and one muscle cell line, associations between IGF-I and activities of caspase 3/7, 8 and 9 have been examined ; the role of insulin-like growth factor I receptor ( IGF-IR ) in the caspase activation has been investigated
Chu et al., Chin J Physiol 2009 (Heart Diseases) : Western blots and TUNEL assay revealed that in the presence of IGF1R , exogenous IGF-II acts, like IGF-I, would increase phospho-Akt through IGF1R, but does not affect the caspase 3 activation and apoptotic induction in H9c2 cardiomyoblast cells