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CASP3 — SMARCC2
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Delaney et al., J Neurobiol 1999
:
Caspase-3 activity was rapidly activated upon serum withdrawal in SC, and the caspase inhibitor
BAF blocked apoptosis
Delaney et al., J Neuropathol Exp Neurol 2001
(Diabetic Neuropathies) :
High glucose induces caspase cleavage in apoptotic SCs -- an effect that is blocked by
bok-asp-fmk (BAF) , a
caspase inhibitor
Zaidi et al., J Neuropathol Exp Neurol 2001
:
Cell death was inhibited by 3-methyladenine, an inhibitor of autophagic vacuole formation, but not by
Boc-Asp-FMK (BAF) , a broad
caspase inhibitor
Bhat et al., J Alzheimers Dis 2002
:
To determine whether these pathways interact from a signalling perspective, we compared the effects of
BAF ( a general
caspase inhibitor ), Li+ ( a GSK3beta inhibitor ) and insulin on NGF-W induced PC12 cell death ...
BAF inhibited
caspase-3 activity and delayed cell death up to 6 h after NGF-W indicating that caspase inhibition is sufficient to prevent apoptosis
Furukawa et al., J Struct Biol 2007
:
This
BAF loss was not detected before drICE activation and was
inhibited by Ac-DEVD-CHO
caspase inhibitors