Thoma-Uszynski et al., J Immunol 2000
:
However, both DN and CD8 ( + ) CTL induced nuclear apoptosis required caspase activation
Ruiz et al., Clin Immunol 2001
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These findings demonstrate that intracellular caspase-1- and -3-like enzyme activity increases in both CD4 ( + ) and CD8 ( + ) alloreactive T cells as the primary response to allostimulatory cells progresses