Verdot et al., Eur J Biochem 1999
:
Taken together, these data suggest that chicken cystatin induces the synthesis of tumor necrosis factor alpha and interleukin 10 Figueiredo et al., FEBS J 2009
(MAP Kinase Signaling System) :
To define the underlying mechanisms, we measured in vitro the production of IL-10 in macrophages in response to cystatin from Acanthocheilonema viteae, an immunomodulatory protein of filarial nematodes, and developed mathematical models of IL-10 regulation
DaniĆowicz-Luebert et al., Int J Parasitol 2013
(Hypersensitivity) :
Ex vivo restimulation with cystatin of spleen cells from cystatin treated mice induced the production of IL-10 , while cystatin inhibited allergen-specific IL-5 and IL-13 levels