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IL12A — MRXS5
Text-mined interactions from Literome
la Sala et al., J Immunol 2001
(Inflammation) :
ATP inhibition of TNF-alpha and
IL-12 production by mature DCs was not
mediated by
PGs or elevation of intracellular cAMP and did not require ATP degradation
Pérez-Santos et al., Parasite Immunol 2001
(Disease Models, Animal...) :
In vitro administration of indomethacin (INDO), a specific inhibitor of
PGs synthesis, reduced PGs production at normal levels, and
increased IL-12 , IFN-gamma, and NO production in infected BALB/c mice
Lawrence et al., Infect Immun 1998
:
The ability of most bacterial
PGs to
induce IL-12 production suggests that they play an important role in triggering host defense mechanisms against bacterial infections