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CASP5 — MAP2K7

Text-mined interactions from Literome

Shiah et al., Mol Pharmacol 2001 : Involvement of Asp-Glu-Val-Asp directed, caspase mediated mitogen activated protein kinase kinase 1 Cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel induced apoptosis in HL-60 cells
Johnson et al., Urology 2002 (Prostatic Neoplasms) : Calcitriol induces poly ( adenosine diphosphate-ribose ) polymerase cleavage, increases bax/bcl-2 ratio, reduces levels of phosphorylated mitogen activated protein kinases ( P-MAPKs ; also known as extracellular signal related kinase [ ERK] 1/2 ) and phosphorylated Akt, induces caspase dependent mitogen activated protein kinase kinase ( MEK ) cleavage and upregulation of MEK kinase-1, all potential markers of the apoptotic pathway
Nesterov et al., Cancer Res 2004 (Cell Transformation, Neoplastic...) : The expression of constitutively activated mitogen activated protein kinase kinase 1 enhanced caspase 8 recruitment and sensitized immortalized human embryonic kidney cells to TRAIL induced death