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Chau et al., Proc Natl Acad Sci U S A 2010
(Obesity) :
Activation of AMPK and SIRT1 by FGF21 in adipocytes enhanced mitochondrial oxidative capacity as demonstrated by increases in oxygen consumption, citrate synthase activity, and induction of key metabolic genes
Nygaard et al., Exp Diabetes Res 2012
:
To study the role of AMPK in the putative regulation of FGF21 , hepatocytes were incubated with Compound C ( an AMPK inhibitor ) in the presence of metformin