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PRKAB1 — SIRT3
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Shi et al., J Dig Dis 2010
:
The
activation of
AMPK by
SIRT3 was dependent on SIRT3 deacetylase activity
Shulga et al., J Cell Sci 2010
:
Moreover, activation of
AMPK , a known positive modulator of sirtuin activity,
prevented the ethanol induced suppression of
sirtuin-3 activity and the attendant increase of cyclophilin-D acetylation, activity and association with ANT-1
Caton et al., Diabetes Obes Metab 2011
(Disease Models, Animal...) :
Metformin
increased AMPK activity in WAT of db/db mice and in metformin treated adipocytes, with increased NAMPT,
SIRT1 and circadian component expression
Li et al., Basic Res Cardiol 2011
:
Parallel to these changes, we observed
AMPK activation,
SIRT1 induction and PGC-1a deacetylation
Greco et al., Biochem Biophys Res Commun 2011
(Alzheimer Disease) :
To this end, we investigated the extent to which
activation of
AMPK as well as another class of sensors linking energy availability to cellular metabolism, the
sirtuins ( SIRT ) , mediate Leptin 's biological activity
Tillu et al., Molecular pain 2012
(Acute Pain...) :
Our results demonstrate that resveratrol profoundly inhibits ERK and mTOR signaling in sensory neurons in a time- and concentration dependent fashion and that these effects are mediated by
AMPK activation and
independent of
sirtuin activity
Peserico et al., Cell Mol Life Sci 2013
:
A novel
AMPK dependent
FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels