Mandal et al., Endocrinology 2009
:
We have recently described the involvement of Smad 1/5 in BMP-2 induced CSF-1 expression and osteoclast formation ... Inhibition of PI3K/Akt signaling blocked the binding of Smads 1/5 to the CSF-1 BMP-responsive element present in the CSF-1 promoter, resulting in attenuation of Smad dependent CSF-1 transcription
Ghosh-Choudhury et al., J Biol Chem 2013
:
c-Abl contributed to BMP receptor-specific Smad dependent transcription of CSF-1 , osterix, and BMP-2