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CASP14 — HSPB1

Text-mined interactions from Literome

Concannon et al., Gene Expr 2001 : Hsp27 inhibits cytochrome c-mediated caspase activation by sequestering both pro-caspase-3 and cytochrome c
Enomoto et al., Int J Radiat Biol 2001 : Prolonged phosphorylation or activation of JNK1 was considered important for heat induced apoptosis and JNK1 may control the process possibly through phosphorylation of HSP27 and caspase-9 activation in U937 cells
Oya-Ito et al., J Cell Biochem 2006 (Cataract) : In vitro incubation experiments showed that MGO modified Hsp27 reduced the activity of caspase-9 , and MGO modified pHsp27 reduced activities of both caspase-9 and caspase-3
Voss et al., J Biol Chem 2007 : Consistent with a central role of Hsp27 in blocking caspase-3 activation, Hsp27 down-regulation by double stranded RNA interference induces apoptosis of macrophages, whereas Hsp27 overexpression increases the life span of monocytes by inhibiting apoptosis
Bao et al., Acta Pharmacol Sin 2010 : The induced HSP27 by bicyclol suppressed the activity of caspase-3 and the phosphorylation of JNK caused by D-GaIN in HepG2 cells
Chan et al., J Virol 2012 : Temporal transcriptome and functional analyses identified heat shock protein 27 (HSP27) and Mcl-1, two known regulators of caspase 3 activation, as being upregulated prior to the 48-h viability gate following HCMV infection