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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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BRCA1 — CHKA

Text-mined interactions from Literome

Kim et al., Mol Cell Biol 2004 (Cell Transformation, Neoplastic...) : To study the functions of CHK2 dependent phosphorylation of BRCA1 , we generated a mouse model carrying the mutation S971A ( S971 in mouse Brca1 corresponds to S988 in human BRCA1 ) by gene targeting
Gibson et al., Radiat Res 2006 : CHK2 dependent phosphorylation of BRCA1 in hypoxia
Chabalier-Taste et al., Biochim Biophys Acta 2008 : BRCA1 is regulated by Chk2 in response to spindle damage
Yarden et al., Int J Biochem Cell Biol 2012 : Previously we showed that BRCA1 is necessary for Chk1 phosphorylation and activation following ionizing radiation ... While Chk1 phosphorylation of S317 is fully dependent on BRCA1 , additional proteins may mediate S345 phosphorylation at later time points