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BRCA1 — NEK2
Text-mined interactions from Literome
Wang et al., J Biol Chem 2004
(Genomic Instability...) :
We demonstrate that small interfering RNA mediated suppression of Brca1 decreased Nek2 more dramatically in Gadd45a ( -/- ) cells than in wild-type cells and, conversely, that overexpression of
Brca1 and/or Gadd45a
up-regulated transcription of
Nek2
Sankaran et al., Cancer Res 2007
:
We show that Aurora-A kinase modulates the
BRCA1 inhibition of
centrosome function by decreasing the E3 ubiquitin ligase activity of BRCA1