Siu et al., Mol Cell Biol 1992
:
Expression of the CD4 gene requires a Myb transcription factor Chen et al., Am J Respir Crit Care Med 2005
(Pleural Effusion, Malignant) :
The increased CD4 ( + ) CD25 ( + ) T cells found in malignant pleural effusion express high levels of Foxp3 transcription factor and potently suppress the proliferation of CD4 ( + ) CD25 ( - ) T cells, and cytotoxic lymphocyte associated antigen-4 is involved in the suppressive activity of pleural CD4 ( + ) CD25 ( + ) T cells
Niederkorn et al., J Immunol 2006
(Dehydration...) :
The results suggest that DS exposes shared epitopes in the cornea, conjunctiva, and LG that induce pathogenic CD4 ( + ) T cells that produce LKC, which under normal circumstances is restrained by CD4 ( + ) CD25 ( + ) forkhead/winged helix transcription factor ( + ) regulatory T cells