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FASLG — MYLIP

Text-mined interactions from Literome

Sayed et al., J Biol Chem 2010 (Myocardial Reperfusion Injury) : In consensus, overexpression of miR-21 in a transgenic mouse heart resulted in suppression of ischemia induced up-regulation of PTEN and FasL expression, an increase in phospho-AKT, a smaller infarct size, and ameliorated heart failure ... Thus, we have identified a unique aspect of the function of AKT by which it inhibits apoptosis through miR-21 dependent suppression of FasL
Buller et al., FEBS J 2010 (Ischemia...) : Moreover, overexpression of miR-21 in neurons significantly reduced FASLG levels, and introduction of an miR-21 mimic into 293-HEK cells substantially reduced luciferase activity in a reporter system containing the 3'-UTR of Faslg
Zhang et al., Urology 2011 (Carcinoma, Renal Cell...) : The reduction of miR-21 inhibited Fas ligand and TIMP3 expression by targeting the binding site within the 3 ' untranslated region
Wang et al., Dig Dis Sci 2013 (Carcinoma, Squamous Cell...) : miR-21 may be involved in the tumorgenesis of ESCC by targeting FASL , TIMP3 and RECK