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MYLIP — PTPN23
Text-mined interactions from Literome
Liu et al., BMC systems biology 2010
(Anoxia...) :
For instance, loss of miR-149, miR-200c and
mir-141 causes gain of function of oncogenes ( KCNMA1, LOX ), VEGFA and SEMA6A respectively and
increased levels of miR-142-3p, miR-185, mir-34a, miR-224, miR-21 cause loss of function of tumor suppressors LRRC2,
PTPN13 , SFRP1, ERBB4, and ( SLC12A1, TCF21 ) respectively
Tanaka et al., J Biol Chem 2013
(Neoplasms, Germ Cell and Embryonal...) :
These data suggest that PTPN23 is a tumor suppressor and that
repression of
PTPN23 expression by
miR-142-3p plays an important role in the pathogenesis of TGCTs