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MAPK9 — NOS3
Text-mined interactions from Literome
Nandan et al., Infect Immun 1999
:
Activation of phosphotyrosine phosphatase activity attenuates
mitogen activated protein kinase signaling and
inhibits c-FOS and
nitric oxide synthase expression in macrophages infected with Leishmania donovani
Maeda et al., J Pharmacol Exp Ther 2000
:
The
endothelial NOS gene transfer did not affect endothelin-1 induced increase in [ Ca ( 2+ ) ] ( i ) of type A receptor transfected cells, but markedly
inhibited mitogen activated protein kinase and c-fos promoter activities
Shaul et al., Semin Perinatol 2000
:
The inhibition of calcium influx, or tyrosine kinases or
mitogen activated protein ( MAP ) kinase prevents
eNOS stimulation by estrogen, and estrogen causes rapid ER-dependent activation of MAP kinase
Xu et al., Life Sci 2000
(Glioma...) :
P38
MAPK , but not p42/p44 MAPK
mediated inducible
nitric oxide synthase expression in C6 glioma cells
Fabrizi et al., J Biol Chem 2001
:
The stimulation of inducible
nitric-oxide synthase by the prion protein fragment 106 -- 126 in human microglia is tumor necrosis factor-alpha dependent and
involves p38
mitogen activated protein kinase
Llansola et al., Brain Res 2002
:
Activation of N-methyl-D-aspartate ( NMDA ) receptors leads to increased phosphorylation of the microtubule associated protein MAP-2 by a mechanism that involves activation of
nitric oxide synthase and nitric oxide induced
activation of
mitogen activated protein kinase ( MAP-kinase )
Simkhovich et al., Cardiovasc Pathol 2003
(Myocardial Ischemia) :
Protective genes included
mitogen activated protein kinase activated protein kinase 3 ( MAPKAPK 3 ), heat shock proteins 70, 27, 22, B-crystalline, vascular endothelial growth factor, inducible
nitric oxide synthase and plasminogen activator inhibitors 1 and 2
Wang et al., J Pharmacol Exp Ther 2003
:
Up-regulation of endothelial
nitric-oxide synthase by endothelium derived hyperpolarizing factor
involves mitogen activated protein kinase and protein kinase C signaling pathways
Kitamura et al., Diabetologia 2003
:
Proinsulin C-peptide increases nitric oxide production by enhancing
mitogen activated protein-kinase dependent transcription of endothelial
nitric oxide synthase in aortic endothelial cells of Wistar rats
Wahren et al., Exp Diabesity Res 2004
:
Binding of C-peptide results in activation of Ca2+ and
MAPK dependent pathways and stimulation of Na+, K ( + ) -ATPase and
eNOS activities
Anter et al., J Biol Chem 2004
:
Activation of endothelial
nitric-oxide synthase by the p38
MAPK in response to black tea polyphenols
Wang et al., Atherosclerosis 2006
:
Inhibitors of PPARalpha, PI3 kinase and
MAPK , respectively, markedly
attenuate bezafibrate induced upregulation of
eNOS
Donnini et al., J Pharmacol Exp Ther 2006
:
Consistently, in cultured coronary endothelial cells ( CVECs ), ACEI up-regulated
endothelial NOS (eNOS) and FGF-2 and
induced mitogen activated protein kinase extracellular signal regulated kinase 1/2 activation
Jiang et al., Prostaglandins Other Lipid Mediat 2007
(MAP Kinase Signaling System) :
However, inhibitors of protein kinase B ( Akt ),
mitogen activated protein kinase ( MAPK ) and MAPK kinase could
block phosphorylation of
eNOS at both sites
Johnson et al., Biol Reprod 2008
:
The protection offered by the caspase 2 inhibitor occurred upstream of mitochondria, involving suppression of
mitogen activated protein kinase ( MAPK) 14 activation and inducible
nitric oxide synthase ( NOS2 )
induction and, in turn, suppression of cytochrome c-mediated death pathway
Chen et al., Mol Biol Rep 2010
(Inflammation...) :
However, the anti-inflammation effects of eNOS in infarcted myocardium and the
role of
MAPK signaling in
eNOS/NO mediated cardiac remodeling have not yet been elucidated ... Phosphorylation of
MAPK after MI were also dramatically
reduced by
eNOS gene transfer
Ralay Ranaivo et al., Brain Res 2010
(MAP Kinase Signaling System) :
Albumin activated ERK1/2, p38
MAPK and JNK signaling pathways in astrocytes, and
induced the production of interleukin (IL)-1beta, inducible
nitric oxide (NO) synthase , the NO metabolite nitrite, and the chemokine CX3CL1 while reducing the level of S100B
Lee et al., Am J Physiol Cell Physiol 2010
(Anoxia) :
Hypoxia induced
endothelial nitric oxide synthase (eNOS) phosphorylation was
regulated by p38
MAPK and SAPK/JNK activation
Erdogdu et al., J Mol Endocrinol 2013
:
Palmitate induced apoptosis stimulated cells to release NO and ROS, concomitant with upregulation of
eNOS , which
required activation of p38
MAPK and JNK
Nishiya et al., FEBS Lett 1997
(Glioma) :
Activation of Stat1 and subsequent transcription of inducible
nitric oxide synthase gene in C6 glioma cells is
independent of interferon-gamma induced
MAPK activation that is mediated by p21ras