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NOS3 — S100A12
Text-mined interactions from Literome
Akiba et al., Am J Physiol Gastrointest Liver Physiol 2001
:
Antagonism of vanilloid and
CGRP receptors,
inhibition of
nitric oxide synthase , and sensory deafferentation delayed gel thickening, suggesting that the capsaicin pathway mediated the initial burst of mucus secretion that thickened the gel
Lee et al., Regul Pept 2003
:
These results suggest that NTG induced
CGRP release is
eNOS dependent and tissue- and gender-selective ... Our study revealed a novel
eNOS dependent interaction between NO and
CGRP , and the possible participation of regulatory peptides in affecting platelet function and possibly cardiovascular protection in females
Wang et al., Am J Physiol Heart Circ Physiol 2004
(Hyperplasia) :
Furthermore,
CGRP gene transfer
increased inducible
nitric oxide synthase and p53 but decreased PCNA and Bcl-2 protein levels in balloon injured rat aorta
Harada et al., Thromb Haemost 2005
(Disease Models, Animal...) :
In this process,
CGRP induced
activation of both endothelial
nitric oxide synthase and cyclooxygenase-1 might be critically involved
Zheng et al., Am J Physiol Cell Physiol 2010
(Ischemia) :
CGRP also
induced endothelial nitric oxide synthase (eNOS) phosphorylation in HUVECs at Ser1177 and Ser633 in a time dependent manner, and such effects were abolished by AMPK inhibitor Compound C
Yoshimoto et al., Br J Pharmacol 1998
:
8. These results suggest that in the rat aorta, adrenomedullin and
alpha-CGRP increase the endothelial [ Ca2+ ] i, activate
nitric oxide synthase and release nitric oxide, without a direct inhibitory action on smooth muscle