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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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NOS3 — SIRT1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Arunachalam et al., Biochem Biophys Res Commun 2010 : However, the role of SIRT1 in regulation of eNOS by CS and oxidants are not known
Centeno-Baez et al., Am J Physiol Endocrinol Metab 2011 : Resveratrol inhibition of inducible nitric oxide synthase in skeletal muscle involves AMPK but not SIRT1
Ye et al., Cardiovasc Drugs Ther 2011 (Diabetes Mellitus, Experimental...) : Both AL and VA reduced myocardial AT1R levels, without affecting AT2R levels, and increased the expression of Sirt1 and PGC-1a with increased phosphorylation of Akt and eNOS
Xia et al., Nitric Oxide 2013 : Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol
Lempiäinen et al., Acta Physiol (Oxf) 2013 (Inflammation...) : As compared with I/R injury group, CR further increased kidney SIRT1 expression by 1.8-fold, promoted autophagy and counteracted I/R induced decreases in the expression of eNOS and PGC-1a