◀ Back to SIRT1
BCL10 — SIRT1
Text-mined interactions from Literome
Hsu et al., Circulation 2010
(Myocardial Reperfusion Injury) :
Sirt1 positively
regulates expression of prosurvival molecules, including manganese superoxide dismutase, thioredoxin-1, and
Bcl-xL , whereas it negatively regulates the proapoptotic molecules Bax and cleaved caspase-3
Seo et al., Neurobiol Aging 2012
:
SIRT1 activation also inhibited PrP ( 106-126 ) -mediated p38 mitogen activating protein kinase ( MAPK ) activation and caspase-3 cleavage, and
increased the expression of anti-apoptotic
Bcl-xL protein