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NOS2 — WNT2
Text-mined interactions from Literome
Rigas et al., Trends Mol Med 2004
(Neoplasms) :
Mechanistically, NO-aspirin, the best studied NO-NSAID, has pleiotropic effects on cell signaling ( it inhibits
Wnt signaling,
induces nitric oxide synthase and NF-kappaB activation and induces cyclooxygenase-2 expression ), and this mechanistic redundancy might be central to its mode of action against cancer
Du et al., Cancer Res 2006
:
Regulation of human
nitric oxide synthase 2 expression by
Wnt beta-catenin signaling
Du et al., Cancer Res 2009
(Neoplasms) :
Wnt/beta-catenin signaling
regulates cytokine induced human inducible
nitric oxide synthase expression by inhibiting nuclear factor-kappaB activation in cancer cells
Freise et al., J Nutr Biochem 2013
(Inflammation...) :
( + ) -Episesamin inhibits adipogenesis and exerts anti-inflammatory effects in 3T3-L1 ( pre ) adipocytes by sustained
Wnt signaling, down-regulation of PPAR? and
induction of
iNOS