Gene interactions and pathways from curated databases and text-mining

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HMGB1 — HMOX1

Text-mined interactions from Literome

Gong et al., Int Immunopharmacol 2008 (Respiratory Distress Syndrome, Adult) : Heme oxygenase-1 upregulation significantly inhibits TNF-alpha and Hmgb1 releasing and attenuates lipopolysaccharide induced acute lung injury in mice
Jun et al., Phytother Res 2012 (Disease Models, Animal...) : Inducers of heme oxygenase-1 (HO-1) reduce high mobility group box?1 (HMGB1) , a late phase cytokine, in sepsis
Fumimoto et al., J Pharmacol Sci 2012 : As one of the molecular mechanisms for the inhibitory effects of kahweol, we also showed that kahweol up-regulated heme oxygenase-1 and inhibited high mobility group box 1 release
Park et al., Food Chem Toxicol 2013 (Inflammation...) : We recently proposed that heme oxygenase-1 (HO-1) negatively regulates HMGB1 in inflammatory conditions
Wang et al., J Surg Res 2013 (Disease Models, Animal...) : Dobutamine mediated heme oxygenase-1 induction via PI3K and p38 MAPK inhibits high mobility group box 1 protein release and attenuates rat myocardial ischemia/reperfusion injury in vivo