◀ Back to IL6
IGF2 — IL6
Text-mined interactions from Literome
Kwon et al., Biochem Biophys Res Commun 2000
(Psoriasis) :
Insulin-like growth factor II induces
interleukin-6 expression via NFkappaB activation in psoriasis ... We found that
IGF-II induced the
IL-6 mRNA expression significantly ... Interestingly,
IL-6 promoter activity and the binding activity of NFkappaB were remarkably
increased by
IGF-II
Tu et al., Cancer Res 2000
(MAP Kinase Signaling System...) :
In correlation with activation of PI 3-K,
IGF-I also effectively activated the AKT kinase in 8226 and OCI-My5 cells, and
IL-6 activated AKT in AF-10 and MH.60 cells
Anwar et al., Circulation 2002
(Arteriosclerosis) :
IL-1beta,
IL-6 , and IFN-gamma did not
regulate IGF-1, IGF-1 receptor (R), or
IGF binding proteins ( IGFBPs )
Perrier d'Hauterive et al., Journal de gynécologie, obstétrique et biologie de la reproduction 2004
:
The molecular basis of the implantation window remains to be defined In the present study, we investigated the
role of hCG, TGFbeta1,
IGF1 and IGF2 in the secretion of leukemia inhibitory factor (LIF) and
interleukin-6 (IL-6) by human epithelial endometrial cells in culture ... The molecular basis of the implantation window remains to be defined In the present study, we investigated the
role of hCG, TGFbeta1, IGF1 and
IGF2 in the secretion of leukemia inhibitory factor (LIF) and
interleukin-6 (IL-6) by human epithelial endometrial cells in culture
Nemet et al., Am J Physiol Regul Integr Comp Physiol 2006
:
The results suggest that
IL-6 plays a role in the GH --
> IGF-I response to intense exercise
Rojas et al., Oncogene 2011
(Cell Transformation, Neoplastic...) :
Moreover, we find that paracrine
IL-6 stimulates the autocrine IL-6 loop and autocrine activation of insulin-like type I growth factor receptor (
IGF-IR ) to confer the tumorigenic property and also that activation of signal transducer and activator of transcription 3 ( STAT3 ) is critical in these processes ... Inhibition of STAT3 activation suppresses
IL-6 induced
upregulation of
IGF-IR and its ligands, namely IGF-I and IGF-II
Jelinek et al., J Immunol 1997
(Multiple Myeloma) :
The specificity of the IGF response was confirmed using an IGF-I receptor Ab, and additional studies demonstrated that
IGF responsiveness did not
result from induction of autocrine
IL-6 expression
Franchimont et al., Endocrinology 1997
:
We tested the
effects of
IL-6 and its soluble receptor (IL-6sR) on the expression of insulin-like growth factor (IGF)-I and
IGF-II in cultured osteoblast enriched cells from fetal rat calvariae ( Ob cells )