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IL6 — MBP
Text-mined interactions from Literome
Haggiag et al., J Neurosci Res 2001
:
IL6RIL6 induces Po and
MBP in CH cells and their cocultures with neurons
Miller et al., Int J Dev Neurosci 2010
(Prenatal Exposure Delayed Effects) :
Instead,
IL-6 may
contribute to increased
MBP levels in males, whereas in females estromimetic and thyromimetic PCB metabolites may affect white matter development
Selmaj et al., Clin Exp Immunol 1988
(Multiple Sclerosis) :
Multiple sclerosis :
effect of
myelin basic protein on
interleukin 1, interleukin 2 production and interleukin 2 receptor expression in vitro
Arai et al., Q J Med 1993
(Acute-Phase Reaction...) :
MBP mRNA expression in HuH-7 cells was
increased by
interleukin-6 (IL-6) , dexamethasone and heat shock, decreased by interleukin 1 (IL-1), and unaffected by interferon gamma (IFN gamma), tumour necrosis factor alpha (TNF alpha) and transforming growth factor beta ( TGF beta )
Rochester et al., J Immunol 1996
:
To test the hypothesis that eosinophil major basic protein (MBP) is an important regulator of fibroblast effector function, we characterized the
effects of
MBP on human lung fibroblast production of the IL-6-type cytokines,
IL-6 , IL-11, and leukemia inhibitory factor ... These studies demonstrate that
MBP interacts in a synergistic fashion with rIL-1-alpha or TGF-beta(1) to further
augment fibroblast
IL-6-type cytokine production