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IL6 — NPY

Text-mined interactions from Literome

Straub et al., J Neurochem 2000 (Synaptic Transmission) : Under these conditions, NPY dose-dependently inhibited IL-6 secretion with a maximum effect at 10 ( -10 ) M : ( p = 0.012 ) and 10 ( -9 ) M : ( p < 0.001 )
Hernanz et al., Regul Pept 2003 (Arthritis, Rheumatoid...) : In the present study, we have investigated the in vitro effect of calcitonin related peptide ( CGRP ), neuropeptide Y (NPY) , substance P ( SP ) and vasoactive intestinal peptide (VIP) at concentrations of 10 ( -8 ), 10 ( -9 ) and 10 ( -10 ) M on the production of different proinflammatory cytokines or chemokines such as IL-1beta, IL-6 and TNFalpha by peripheral whole blood cells from patients with rheumatoid arthritis, as well as from osteoarthritis patients studied as a control group without immunoinflammatory background
Singer et al., PloS one 2013 (Inflammation...) : NPY receptor inhibition promoted DC maturation and the production of IL-6 and TNFa suggesting an anti-inflammatory function for NPY signaling in DCs
Zhou et al., J Neuroimmunol 2013 (MAP Kinase Signaling System) : In the present work, we have evaluated the effects of NPY on the release of TNF-a, IL-1ß, IL-6 and HMGB1 mediators in peritoneal macrophages ... Our results demonstrate for the first time that NPY can directly induce active HMGB1 release and cytoplasmic translocation, while the production of TNF-a, IL-1ß and IL-6 is not affected
Pazos et al., PloS one 2013 : Il6 deficiency during this stage up-regulated Npy and Agrp expression, while restoring Pomc mRNA levels to virgin values
Hernanz et al., J Neuroimmunol 1996 : Differential effects of gastrin releasing peptide, neuropeptide Y , somatostatin and vasoactive intestinal peptide on interleukin-1 beta, interleukin-6 and tumor necrosis factor-alpha production by whole blood cells from healthy young and old subjects ... In the present study, we have investigated the effect in vitro of gastrin releasing peptide ( GRP, 10 ( -10 ) M ), neuropeptide Y ( NPY, 10 ( -10 ) M ), somatostatin ( 10 ( -10 ) M ) and vasoactive intestinal peptide ( VIP, 10 ( -9 ) M ) on the production of IL-1 beta, IL-6 and TNF alpha by peripheral whole blood cells from healthy young and old people ... In addition, the production of IL-6 was enhanced by GRP, NPY and VIP in young and old people