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PTBP1 — STAT3

Text-mined interactions from Literome

Nagayama et al., J Immunol 2000 : Receptor engagement of DCs as well as Con A blasts by IL-12 resulted in activation of Janus kinase 2 and Tyk2 kinases and Stat3 and Stat4 transcription factors and the association of these proteins to IL-12Rbeta1
Nefedova et al., J Immunol 2005 : Surprisingly, inhibition of Jak2/STAT3 signaling resulted in dramatic activation of immature DCs generated in the presence of TDF as well as in control medium
Kitamura et al., Immunity 2005 : Here, we showed that IL-6-STAT3 signaling reduced intracellular MHCII alphabeta dimmer, Ii, and H2-DM levels in DCs ... Overexpression of cystatin C suppressed IL-6-STAT3 mediated increase of cathepsin S activity and reduction of MHCII alphabeta dimer, Ii, and H2-DM levels in DCs
Li et al., J Immunol 2006 (Encephalomyelitis, Autoimmune, Experimental) : Indeed, in the present study we found that bone marrow derived DCs transduced with SOCS-3 significantly inhibited IL-12 induced activation of Stat4 and IL-23 induced activation of Stat3
Lifshitz et al., Mol Immunol 2009 : The inability to detect EPO mediated activation of STAT5 in the BM-DCs, suggests that in DCs , STAT3 may play a more important role than STAT5 in EPO-R signaling
Yi et al., Blood 2009 : These findings demonstrate that AC-induced inhibition of DCs requires MerTK dependent activation of c-Src and STAT3 , and provide evidence for novel roles for c-Src and STAT3 in the immunoregulation of DCs
Melillo et al., J Immunol 2010 (Crohn Disease...) : These results reveal a cell-intrinsic negative regulatory role of Stat3 in DCs and link increased DC activation with perturbed immune homeostasis and chronic mucosal inflammation
Nieminen et al., PloS one 2013 : We found that IL-6- and IFN-a induced STAT3 phosphorylation and IFN-a induced STAT1 phosphorylation were impaired in plasmacytoid DCs ( pDCs ) from CD patients ( P?=?0.005, P?=?0.013, and P?=?0.006, respectively )