◀ Back to IL7

AKT2 — IL7

Text-mined interactions from Literome

Barata et al., Blood 2004 (Disease Progression...) : Stimulation of TAIL7 cells by IL-7 leads to phosphorylation of Janus kinase 3 (JAK3), signal transducer and activator of transcription 5 ( STAT5 ), Akt/PKB ( protein kinase B ), and extracellular regulated kinase 1 and 2 ( Erk1/2 )
Barata et al., J Exp Med 2004 (Precursor Cell Lymphoblastic Leukemia-Lymphoma) : IL-7 induced PI3K dependent phosphorylation of Akt and its downstream targets GSK-3, FOXO1, and FOXO3a
Barata et al., Leukemia & lymphoma 2005 (Leukemia-Lymphoma, Adult T-Cell) : IL-7 induces the activation of Jak/STAT, MEK/Erk and PI3K/Akt signaling pathways in T-ALL cells
Venkatachalam et al., Am J Physiol Heart Circ Physiol 2008 (Hyperglycemia) : Resveratrol inhibits high glucose induced PI3K/Akt/ERK dependent interleukin-17 expression in primary mouse cardiac fibroblasts
Johnson et al., J Immunol 2008 : IL-7 stimulation of CD34 ( + ) immature thymocytes led to phosphorylation ( p- ) of STAT5, ERK1/2, AKT, and glycogen synthase kinase-3 beta, and increased AKT enzymatic activity ... IL-7 stimulation of rested CD19 ( + ) cells resulted in robust induction of p-ERK1/2, but no induction of AKT enzymatic activity
Lazorchak et al., Mol Cell 2010 : We further show that Akt2 specifically mediates the Sin1-mTORC2 dependent suppression of il7r and rag gene expression in B cells by regulating FoxO1 phosphorylation
Pan et al., Biochem Biophys Res Commun 2012 (Breast Neoplasms) : Mechanistically, we found that IL-7d5 induced the activation of Akt