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LYN — TP53
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Bezombes et al., Mol Pharmacol 2002
:
We demonstrate that PKCzeta inhibited p53/p56 Lyn phosphorylation and stimulation in drug- or H ( 2 ) O ( 2 ) -treated cells, suggesting that
p53/p56 Lyn redox
regulation is altered in PKCzeta overexpressing cells
Ren et al., Cancer Biol Ther 2002
:
Lyn increases
p53 levels and stimulates p53 mediated transcription by a kinase independent mechanism ... The results also demonstrate that
Lyn increases nuclear levels of ubiquitinated
p53 by inhibiting export of p53 to the cytoplasm