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RASSF1 — TP53
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Tian et al., PloS one 2011
:
Moreover,
p53 binding to the promoter
down-regulated RASSF1A expression
Lei et al., Mol Med Report 2013
:
HPV16 infection regulates
RASSF1A transcription
mediated by
p53 ... Similarly, knockdown of endogenous HPV16-E6 in SiHa cells with RNA interference ( RNAi ) led to downregulation of
RASSF1A mediated by
p53 and the subsequent induction of apoptosis ... These findings collectively suggest that HPV16 infection regulates
p53 mediated
RASSF1A expression and suppresses apoptosis