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MAPK13 — RPS6KA1

Pathways - manually collected, often from reviews:

• WikiPathways Insulin Signaling: MINK1/MAP4K4/MAP3K2/MAPK12/MAP3K5/MAPK10/MAP3K3/MAP4K1/MAPK3/MAP2K7/MAPK13/MAP3K1/MAP4K3/MAP2K6/MAP3K8/MAP3K12/MAP2K4/MAPK7/MAPK14/MAP3K11/MAP3K7/MAPK11/MAPK9/MAPK6/MAP3K13/MAP2K3/MAPK4/MAP4K2/MAP2K5/MAP3K10/MAPK1/MAP2K1/MAP3K6/MAP3K4/MAP3K9/MAP4K5/MAP2K2/MAPK8/MAP3K14 → RPS6KA4/RPS6KA3/RPS6KA6/RPS6KA5/RPS6KA1/RPS6KA2 (activation)
  
• WikiPathways Angiopoietin Like Protein 8 Regulatory Pathway: MAP2K1/MAP3K7/MAPK14/MAPK1/MAP2K2/MAP3K2/MAP3K6/MAPK8/MAP4K1/MAP3K11/MAP4K3/MAPK10/MAP2K7/MAP3K4/MAP3K1/MAP3K12/MAPK4/MAPK11/MAP4K5/MAPK6/MAP4K4/MAPK3/MAP3K14/MAPK12/MAP2K5/MAP2K4/MAPK13/MAP3K5/MAPK9/MAPK7/MAP3K3/MAP3K9/MAP3K8/MAP2K6/MAP3K13/MAP4K2/MAP2K3/MAP3K10/MINK1 → RPS6KA5/RPS6KA6/RPS6KA4/RPS6KA1/RPS6KA2/RPS6KA3 (activation)
  

Text-mined interactions from Literome

Butcher et al., Eur J Neurosci 2004 (MAP Kinase Signaling System) : In vivo pharmacological inhibition of light induced MAPK pathway activation blocked RSK-1 phosphorylation, indicating that RSK-1 activity is regulated by the MAPK pathway
Larrea et al., Proc Natl Acad Sci U S A 2009 (MAP Kinase Signaling System) : Because RSK1 is also activated by MAPK , the increased cell motility and metastatic potential of cancer cells with PI3K and/or MAPK pathway activation may result in part from RSK1 activation, leading to accumulation of p27T198 in the cytoplasm, p27 : RhoA binding, inhibition of RhoA/Rock pathway activation, and loss of actomyosin stability