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IFNG — TLR3

Text-mined interactions from Literome

Miettinen et al., Genes Immun 2001 : IFN-gamma enhanced the expression of TLR1 and TLR2 mRNA in macrophages, and TLR3 in epithelial and endothelial cells
Pai et al., Infect Immun 2004 : Microarray gene expression studies were then used to determine whether prolonged TLR signaling by M. tuberculosis broadly inhibits IFN-gamma regulation of macrophage gene expression
Farina et al., J Neuroimmunol 2005 : Quantitative PCR for TLRs 1 to 10 showed a basal expression of TLR3 that could be enhanced by IFN-gamma , IL-1beta, and IFN-beta
Mueller et al., J Immunol 2006 : The down-regulatory effect of Th2 cytokines on TLR expression and function in IECs also counteracted enhanced TLR signaling induced by stimulation with the hallmark Th1 cytokine IFN-gamma
Eriksson et al., J Immunol 2006 : However, purified uNK cells did not respond directly to TLR agonists, but IFN-gamma was produced by uNK cells in response to TLR stimulation when cocultured with APCs
Velayudham et al., J Hepatol 2006 (Granuloma...) : IFNgamma induction by P. acnes, TLR2 and TLR9 ligands required MyD88
Ramakers et al., Cytokine 2006 : In more detail, CPA potentiated TLR5 mediated IL-6 production, TLR3 mediated IFN-gamma production and TLR3 mediated Il-1beta production compared to TLR4 mediated stimulation
Tabiasco et al., J Immunol 2006 : These results thereby suggest that TLR3 ligands can not only indirectly influence the adaptive immune response through modulation of dendritic cell activation, but also directly increase IFN-gamma production by Ag-specific CD8+ T cells
Girart et al., J Immunol 2007 (Melanoma) : Engagement of TLR3, TLR7 , and NKG2D regulate IFN-gamma secretion but not NKG2D mediated cytotoxicity by human NK cells stimulated with suboptimal doses of IL-12
Barr et al., Eur J Immunol 2007 : In this study, we investigated which mouse B cell subsets are the most potent cytokine producers, and examined the role of Toll-like receptors ( TLR ) in the control of secretion of IL-6, IL-10, IL-12 and IFN-gamma by B cells ... Thus, in response to combined TLR stimulation, or via phorbol esters, IFN-gamma was secreted
Allam et al., J Allergy Clin Immunol 2008 : Moreover, TLR4-ligation on oLCs induced IL-10, TGF-beta1, Forkhead box protein 3, IFN-gamma , and IL-2 production in T cells
O'Mahony et al., International journal of medical sciences 2008 : Of the cytokines examined, IFN-gamma and GM-CSF caused the greatest effects on TLR expression
Kleinman et al., Nature 2008 (Macular Degeneration...) : Non targeted ( against non-mammalian genes ) and targeted ( against Vegfa or Vegfr1 ) siRNA suppressed CNV via cell-surface toll-like receptor 3 (TLR3) , its adaptor TRIF, and induction of interferon-gamma and interleukin-12
Beetz et al., Immunobiology 2008 : We have demonstrated expression of TLR3 in Vgamma9Vdelta2 T cells and striking costimulatory effects of the ligand polyinosinic-polycytidylic acid ( polyI : C ) on TCR stimulated IFN-gamma production
Prescott et al., J Allergy Clin Immunol 2008 (Hypersensitivity...) : Maternal allergy ( n = 59 ) was associated with significantly higher neonatal IL-12 and IFN-gamma responses to TLR2, TLR3 , and TLR4 activation, whereas TNF-alpha and IL-6 responses to TLR2, TLR4, and TLR5 activation were significantly higher in newborns who subsequently had allergic disease ( n = 32 )
Archer et al., Cell Microbiol 2009 : Thus, MyD88 dependent innate immune responses induced by L. pneumophila involve both TLR dependent responses and IL-18R dependent production of IFN-gamma by natural killer cells, and these MyD88 dependent pathways can function independently to provide host protection against an intracellular pathogen
Yarovinsky et al., J Immunol 2008 (Acute Disease...) : We further show that this immunopathology is the result of non-TLR dependent activation of IFN-gamma secretion by NK cells in response to the infection
Lotter et al., PLoS Pathog 2009 (Disease Models, Animal...) : IFN-gamma production by NKT cells requires the presence of CD1d and simultaneously TLR receptor signalling through MyD88 and secretion of IL-12
Devilder et al., J Immunol 2009 : Moreover TLR induced Vgamma9Vdelta2 IFN-gamma noncytolytic response led to efficient DC polarization into IL-12p70 producing cells
Lee et al., J Parasitol 2010 : We also performed reverse transcriptase-polymerase chain reaction ( RT-PCR ) and flow cytometry to determine whether TLR and MUC expression is regulated by interferon (IFN)-gamma , interleukin-4, or monoclonal antibodies ( mAbs ) against G. seoi 46 kDa antigen
van Hoffen et al., Int Arch Allergy Immunol 2010 : Apically added LGG, TLR2 and NOD2 ligands, but not Bb, enhanced IFN-gamma , IL-12 and/or TNF-alpha secretion
Tournadre et al., Arthritis Rheum 2010 (Dermatomyositis...) : Stimulation with interferon-gamma (IFNgamma) increased TLR-3 mRNA levels, but IL-17 down-regulated the inducing effect of IFNgamma
Fang et al., FEMS Immunol Med Microbiol 2010 (West Nile Fever) : Viral antigens were detected in WNV infected gammadelta T cells.WNV infection or toll-like receptor ( TLR ) agonist treatment of gammadelta T cells induced the production of IFN-gamma , tumor necrosis factor-alpha and IL-6, which are known to promote DC maturation
Ahmad et al., J Immunol 2010 : IFN-gamma also induced the expression of TLR3 , melanoma differentiation associated gene 5, and retinoic acid-inducible gene I dsRNA receptors
Brisbin et al., Benef Microbes 2012 : The results demonstrated that chicken CD4+ and CD8+ T-cells express TLR21 and that the various isolates of lactobacilli differentially induces the expression of interleukin 10, interferon-gamma and transforming growth factor beta