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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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CPA1 — INS

Text-mined interactions from Literome

Gerwins et al., J Biol Chem 1992 (Leiomyosarcoma) : ATP and CPA had supraadditive effects on Ins ( 1,4,5 ) P3 accumulation and CPA increased ATP induced Ins ( 1,4,5 ) P3 accumulation in a concentration dependent manner with an EC50 of 3 nM, a concentration which per se had little or no effect on Ins ( 1,4,5 ) P3 accumulation
Abebe et al., Am J Physiol 1998 (Asthma...) : The CPA induced Ins ( 1,4,5 ) P3 production observed in the allergic rabbit tissues was also inhibited by the adenosine-receptor antagonist 8- ( p-sulfophenyl ) -theophylline, suggesting that the effect was mediated by A1 adenosine receptors ... In this preparation, the Gi-Go inhibitor pertussis toxin ( PTX ) attenuated the CPA induced Ins ( 1,4,5 ) P3 accumulation, providing evidence that the generation of Ins ( 1,4,5 ) P3 by A1 adenosine-receptor stimulation is coupled to a PTX-sensitive G protein ( s )