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INS — UCN3
Text-mined interactions from Literome
Li et al., Endocrinology 2003
:
Furthermore,
Ucn III stimulated glucagon and
insulin release from isolated rat islets, and astressin ( 2 ) -B abolished the effects of Ucn III, in keeping with a CRFR2 mediated mechanism ... Taken together, the present studies suggest pancreatic
Ucn III acting through CRFR2 is
involved in the local regulation of glucagon and
insulin secretion
Li et al., Proc Natl Acad Sci U S A 2007
(Diabetes Mellitus, Type 2) :
Here we report the investigation of the hypothesis that endogenous
Ucn 3 regulates
insulin secretion, particularly in the presence of nutrient excess