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IL12B — JAG1
Text-mined interactions from Literome
Wang et al., J Immunol 2000
(Multiple Sclerosis) :
IL-12 is a proinflammatory cytokine secreted by dendritic cells in
response to microbial
Ags and mitogens
Scanga et al., J Immunol 2002
(Toxoplasmosis, Animal) :
Defective
IL-12 responses to T. gondii
Ags ( soluble tachyzoite Ag ( STAg ) ) were observed in MyD88 ( -/- ) peritoneal macrophages, neutrophils, and splenic dendritic cells ( DC )
Weijzen et al., J Immunol 2002
:
Furthermore, coculture of DCs with cells expressing Notch ligand
Jagged-1 induced up-regulation of maturation markers,
IL-12 production, T cell proliferative responses, and IFN-gamma production
Kato et al., Pathobiology 2005
:
T-cell activity and the level of IFN-gamma, IL-10 and
IL-12 expression in rp30 immunized T cells were considerably increased in the
presence of rp30
Ags
Acevedo et al., Vaccine 2006
:
AGs also
induced the production of
IL-12 and nitric oxide ( NO ) in the U937 human histiocyte and J774 mouse macrophage cell lines, respectively