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FOSL1 — MMP9

Text-mined interactions from Literome

Zhang et al., Am J Physiol Lung Cell Mol Physiol 2004 (MAP Kinase Signaling System) : In contrast, Fra-1 had the opposite effect on matrix metalloproteinase (MMP)-9 promoter activity
Belguise et al., Oncogene 2005 (Breast Neoplasms...) : Fra-1 regulated several genes, implicated in invasion, angiogenesis and cell proliferation independently of beta1-integrin activation, and directly induced MMP-1 and MMP-9 promoter activity
Chandrasekar et al., J Biol Chem 2006 (Atherosclerosis) : Ectopic expression of p65, c-Fos, c-Jun, and Fra-1 induced MMP9 promoter activity
Song et al., Mol Immunol 2008 (Neoplasm Invasiveness) : Fra-1 and Stat3 synergistically regulate activation of human MMP-9 gene ... Whether MMP-9 expression is regulated by Fra-1 has been contradictory ... Our study demonstrated that the activation of MMP-9 promoter is dependent upon interactions of Fra-1/c-Jun with Stat3
Adiseshaiah et al., J Cell Physiol 2008 (Lung Neoplasms...) : Ectopic Fra-1 markedly stimulates MMP-2 and MMP-9 mRNA expression ... Furthermore, Fra-1 induced EGFR phosphorylation in an MMP dependent manner, and an EGFR-specific inhibitor was able to block Fra-1 enhanced cell motility and invasion
Tacon et al., J Immunol 2012 (MAP Kinase Signaling System...) : Rhinovirus induced MMP-9 expression is dependent on Fra-1 , which is modulated by formoterol and dexamethasone ... These data indicate that HRV induced activation of the MEK/ERK MAPK pathway and Fra-1 expression are necessary for the upregulation of MMP-9 and can be modulated by two distinct but commonly used asthma pharmacotherapies
Lan et al., J Virol 2012 (Epstein-Barr Virus Infections...) : Notably, LMP2A promoted invasion of NPC cells was blocked when MMP9 expression, Fra-1 induction , or ERK1/2 activation was inhibited