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BCL9 — PARP4
Text-mined interactions from Literome
Jang et al., Biochem Biophys Res Commun 2002
:
The L-canavanine induced caspase-3 activation, degradation of
PARP , and apoptotic DNA fragmentation were
suppressed by ectopic expression of Bcl-2 or
Bcl-xL , both of which are known to play roles as anti-apoptotic regulators
Kawano et al., Anticancer Res 2004
(MAP Kinase Signaling System) :
The combination treatment activated caspase-3 and cleaved
PARP , but it did not
induce any notable change in the expression of
Bcl-XL , Bcl-2 and Bax compared with each single treatment
Ibrado et al., Cancer Res 1996
:
In the present studies, we determined the
effect of high intracellular levels of the antiapoptosis Bcl-2 or
Bcl-xL protein on Yama protease activation and
PARP degradation during Ara-C induced apoptosis ... High Bcl-2 and
Bcl-xL levels in these cells also
inhibited Yama protease activity,
PARP degradation, and apoptosis due to clinically relevant concentrations of etoposide and mitoxantrone