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ARF6 — NPM1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Korgaonkar et al., Mol Cell Biol 2005
:
These data suggest that
NPM inhibits
ARF 's p53 dependent activity by targeting it to nucleoli and impairing ARF-Mdm2 association
Haindl et al., EMBO Rep 2008
:
SENP3 catalyses desumoylation of NPM1-SUMO2 conjugates in vitro and counteracts
ARF induced modification of
NPM1 by SUMO2 in vivo
Brady et al., Oncogene 2009
(Breast Neoplasms...) :
Given our previous finding that ARF directly binds NPM, impeding its transit to the cytoplasm and arresting cells before S-phase entry, we hypothesized that
ARF might also
inhibit NPM phosphorylation ... However,
ARF induction did not
impair phosphorylation of the cdk2 target residue in murine
NPM , Thr198
Saporita et al., Cancer Res 2011
(Cell Transformation, Neoplastic) :
ARF inhibited the interaction between DDX5 and
nucleophosmin (NPM) , preventing association of DDX5 with the rDNA promoter and nuclear pre-ribosomes
Chao et al., J Mol Med (Berl) 2013
(Endometrial Neoplasms) :
The overexpression of the
alternate reading frame ( ARF ) suppressed the estrogen induced increase in the
NPM/B23 protein levels, indicating that ARF inhibited the observed estrogen mediated NPM/B23 stabilization