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MAP3K7 — RCAN1
Text-mined interactions from Literome
Liu et al., Nat Cell Biol 2009
:
Overexpression of
TAK1 and TAB1, or active TAK1 ( DeltaN ),
promoted direct phosphorylation of
RCAN1 in vitro and in vivo ... These results describe a signalling relationship between two central regulatory pathways in which TAK1-TAB1-TAB2 selectively
induces calcineurin-NFAT signalling through direct phosphorylation of
RCAN1 , while calcineurin activation diminishes
TAK1 signalling by dephosphorylation of TAK1 and TAB1
Lee et al., Biochim Biophys Acta 2009
:
DSCR1-1S also
stimulated IL-1R mediated signaling pathways,
TAK1 activation, NF-kappaB transactivation, and IL-8 production, all downstream consequences of IL-1R activation