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NOX3 — PTPN11
Text-mined interactions from Literome
Sampaio et al., Hypertension 2007
:
Ang II-induced phosphorylation of c-Src, extracellular signal regulated kinase ( ERK ) 1/2, and
SHP-2 and
activation of
NAD ( P ) H oxidase were assessed in the absence and presence of Ang- ( 1-7 ) ( 10 ( -6 ) mol/L, 15 minutes ) by immunoblotting and lucigenin enhanced chemiluminescence, respectively
Tabet et al., Circ Res 2008
(Hypertension) :
Ang II increased
SHP-2 phosphorylation and activity with blunted responses in SHRs. Ang II-induced SHP-2 effects were
inhibited by valsartan ( AT(1)R blocker ), apocynin (
NAD ( P ) H oxidase inhibitor ), and Nox1 siRNA