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CD8A — NOTCH1

Text-mined interactions from Literome

Fowlkes et al., J Immunol 2002 : Thus, data from two different Notch1IC transgenic lines indicate that Notch activity promotes CD8 and inhibits CD4 SP development
Hunt et al., Mol Cell Biol 2011 : This defect was recapitulated in vitro as Mtg16 ( -/- ) Lineage ( - ) /Sca1 ( + ) /c-Kit ( + ) ( LSK ) cells of the bone marrow or DN1 cells of the thymus failed to produce CD4 ( + ) /CD8 ( + ) cells in response to a Notch signal
Kuijk et al., Blood 2013 (Neoplasms) : These data indicate that Notch signaling controls human CD8 ( + ) T cell priming and also influences effector T cell functions